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HomeUPSC Mains Question BankUPSC Mains GS 3 Questions BankHow can advances in biotechnology, such asCRISPR gene editing, impact agricultural sustainability,...

How can advances in biotechnology, such asCRISPR gene editing, impact agricultural sustainability, improve human health through personalized medicine, and influence ethical considerations in genetic modification practices?


1. Influence on Agricultural Sustainability

Biotechnology, especially CRISPR gene modification, harbors the ability to transform agriculture in India, where farming is essential for both the economy and the livelihoods of many.

  • Crop Tolerance: CRISPR can facilitate the creation of crops that withstand drought, salinity, and infestations. Recently, Punjab Agricultural University developed a CRISPR-altered variety of rice exhibiting enhanced resistance to abiotic challenges.
  • Increased Productivity: By modifying genes linked with growth and output, it is possible to attain superior yields. Research from the Indian Institute of Horticultural Research produced cucumber varieties that yield 50% more fruit following CRISPR interventions.
  • Decrease in Chemical Usage: Gene editing can produce pest-resistant crops, reducing dependence on harmful chemicals. For instance, farmers in Maharashtra have reported a 30% cutback in pesticide expenses using genetically altered cotton.
  • Bioenhancement: CRISPR allows for the enrichment of primary crops with crucial nutrients. A recent project in Uttar Pradesh fortified iron and zinc levels in wheat via genetic adaptations, tackling malnutrition concerns.
  • Adaptation to Climate Changes: Advancements in biotechnology support crop adaptation to shifting climate scenarios, safeguarding food supplies. An initiative in Karnataka concentrated on reviving ancient millet varieties through genetic modifications that are more resilient to climate variations.

2. Advancing Human Health through Personalized Medicine

Biotechnology, encompassing CRISPR, is pivotal in enhancing healthcare by customizing treatments according to individual genetic makeups.

  • Genomic Analysis: Firms like MedGenome in India are employing genomic assessments to pinpoint disease predispositions, permitting individualized health management approaches.
  • Directed Therapies: CRISPR is fostering the development of targeted therapies for genetic disorders such as Thalassemia and Sickle Cell Anemia, offering potential cures that tackle the fundamental causes of these conditions.
  • Customized Drug Effects: Pharmacogenomics is broadening our comprehension of how individuals react to medicines, resulting in more efficient treatment strategies. This is observable in the cancer treatment regimens at Tata Memorial Hospital in Mumbai.
  • Vaccine Innovation: Biotechnology companies in South Asia are innovating mRNA vaccines, alongside ongoing studies regarding CRISPR-altered vaccines, which could significantly change strategies for future health crises.
  • Restorative Medicine: CRISPR’s gene editing capabilities are driving progress in stem cell therapies, fostering personalized restorative treatments for ailments like spinal cord injuries.

3. Shaping Ethical Considerations

The capabilities of genetic modification introduce a range of ethical challenges that warrant thorough consideration within the Indian context.

  • Oversight Framework: India has set up a Biotechnology Regulatory Authority of India (BRAI) to supervise genetically modified organisms (GMOs), assuring public safety while encouraging innovation.
  • Public Awareness: Misleading information regarding GMOs can provoke public unease. Educational initiatives are essential to cultivate acceptance grounded in scientific data.
  • Fair Access: There exists a possibility that advanced biotechnology may exacerbate disparities between wealthy farmers and small-scale producers unless policies guarantee fair access to biotechnological advancements.
  • Ecological Issues: The prolonged implications of CRISPR-modified organisms on biodiversity and ecosystems require monitoring to avert unintentional repercussions.
  • Informed Agreement: As gene editing technologies for humans become feasible, it will be crucial to strictly uphold the principle of informed consent, preventing misuse and fostering ethical norms.

Conclusion

Progress in biotechnology, particularly CRISPR gene modification, possesses tremendous potential to reshape Indian agriculture, healthcare, and the ethical landscape concerning genetic alterations. With careful execution, biotechnology can greatly enhance agricultural sustainability and personalized healthcare while addressing ethical challenges and public apprehensions. The focus must be on responsible innovation, ensuring that these advancements benefit every segment of society.

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